CMS CPT codes for FDA authorized Bebtelovimab

Feb. 21, 2022

On February 11, the FDA authorized the emergency use of the monoclonal antibody bebtelovimab for the treatment of mild-to-moderate COVID-19 in adult and pediatric patients when all of these apply:

  • They have a positive COVID-19 test result
  • They’re at high-risk for progression to severe COVID-19
  • Alternative COVID-19 treatment options approved or authorized by the FDA aren’t accessible or clinically appropriate for them

CMS created new codes, effective February 11:

Q0222:

  • Long descriptor: Injection, bebtelovimab, 175 mg
  • Short descriptor: Bebtelovimab 175

M0222:

  • Long Descriptor: Intravenous injection, bebtelovimab, includes injection and post administration monitoring
  • Short Descriptor: Bebtelovimab injection

M0223:

  • Long Descriptor: Intravenous injection, bebtelovimab, includes injection and post administration monitoring in the home or residence; this includes a beneficiary’s home that has been made provider-based to the hospital during the COVID-19 public health emergency
  • Short Descriptor: Bebtelovimab injection home

CMS release

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